Input a UniProt ID to identify its subgroup/"diced" cluster.
For subgroups that are not "diced" (SSNs as a function of increasing alignment score), the search opens the Explore page for the subgroup that contains the user-specified UniProt ID.
For "diced" subgroups, the search identifies the cluster in each "diced" SSN that contains the ID (≥3 UniRef IDs/nodes). The number of UniProt IDs, number of cluster nodes, and UniProt ID convergence ratio (CR; described on the Subgroups tab) are provided for each identified cluster.
In the generation of the megaclusters and clusters, some UniProt IDs for singletons may be deleted. The Search will report: "ID not found".
Input a sequence to find subgroups/"diced" clusters that contain homologues. The sequence is used to query the HMMs for the subgroups/"diced" clusters (≥3 UniRef IDs/nodes).
The results reports matches for the "top" three subgroups/"diced" clusters if the e-value is ≤1e-10. The cluster is a link to the Explore page for the cluster.
For "diced" subgroups (SSNs as a function of increasing alignment score), the second section reports matches for clusters in the "diced" SSNs; the clusters with the three smallest e-values are listed. The number of UniProt IDs, number of cluster nodes, and UniProt ID convergence ratio (CR; described on the Subgroups tab) are provided for each identified cluster.
The "Exploring Subgroups" subtab under the "Functionally Diverse Subgroups" tab provides advice about interpreting the search results for these subgroups.
Input the genus/species/strain for an organism.
If only the genus is entered, a pop-up list of matching genus-species-strains is provided for selection of the desired genus/species/strain. If the genus and species are entered, a pop-up list of matching genus-species-strains is provided for selection of the desired genus/species/strain.
The search provides a list of organism’s sequences in the RSS. The list provides the UniProt ID (link to the UniProt page for sequence), Cluster [link to the Explore page(s) containing the UniProt ID], organism name, and UniProt annotation status (SwissProt or TrEMBL).